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The international journal of biochemistry & cell biology
Gradual Weight Loss: Its tempting to go for the quick fix but try and aim for a gradual and sustainable weight loss approach to minimise the risk of significant facial changes
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Pilch H, Mller WE
Complementing this, a 2024 review on NLRP3 therapeutics in DR highlighted new inhibitors like tonabersat, which block P2X7R-mediated ATP signaling in retinal microglia, decreasing IL-1/IL-18 release and microglial polarization to hinder progression from early NPDR to proliferative stages (44)
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