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The mechanism underlying Dihexas effects appears to involve its action as an HGF/c-Met receptor agonist

doi: 10.1016/j.canlet.2003.12.007 129 JuanCAPrez de la LastraJMPlouFJPrez-LebeaE

pylori infection status and CRC development with an OR of 1.89

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performed Gpx4 knockout in mouse myeloid immune cell subpopulations, and the development and homeostasis of tissue-resident macrophages in the lung, peritoneum, spleen, and bone marrow (considered as M0 state) were unaffected [95]