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Missing data were imputed from retrieved subjects of the same randomized treatment arm (RD-MI) 1Model based estimates based on an analysis of covariance model including treatment (and stratification factors for Study 3 only) as a factor and baseline value as a covariate 2Not included in the pre-specified hierarchical testing (except HbA1c for Study 3) 3Model based estimates based on a mixed model for repeated measures including treatment (and stratification factors for Study 3 only) as a factor and baseline values as a covariate 4Baseline value is the geometric mean Missing data were imputed from retrieved subjects of the same randomized treatment arm (RD-MI) 1Model based estimates based on an analysis of covariance model including treatment as a factor and baseline value as a covariate 2Not included in the pre-specified hierarchical testing 3Model based estimates based on a mixed model for repeated measures including treatment as a factor and baseline values as a covariate 4Baseline value is the geometric mean Table 12

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GLP-1 Receptor Agonists - Podcast Version GLP-1 (glucagon-like peptide-1) receptor agonists are injectable medicines used for the treatment of type 2 diabetes and, more recently, for weight management