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[14] [15] Additional symptoms may include glossitis (a sore, red tongue), angular cheilitis (cracks at the corners of the mouth), and gastrointestinal disturbances

All of them contain significant risks," said gastrointestinal surgeon, Dr

That breadth matters because phase 3 trials test efficacy and safety in larger, more representative populations than phase 2 and weight-loss figures often moderate as populations widen

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Injectable routes typically allow lower doses with more reproducible pharmacokinetic profiles