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maintaining adequate fluid intake is important, and renal function should be monitored if severe vomiting or diarrhoea occurs Thyroid concerns : The MHRA advises caution regarding potential risks of thyroid tumours based on animal studies, though there is no confirmed evidence of increased thyroid cancer risk in humans at therapeutic doses

The North American trial treated 127 patients: a loading dose of 200 mg degarelix followed by monthly maintenance of 60 or 80 mg 35

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P = 0.001) but not metformin (MD = 0.04

Often a sign of over-dilution, under-dosing, or incorrect placement

Individual response varies significantly based on genetic predisposition, baseline metabolism, and adherence to lifestyle modifications