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Notes Obesity and weight-related comorbidities Nearly three billion people worldwide are estimated to be living with obesity or overweight (BMI 27 kg/m 2 ), and with rates rapidly rising, effective, accessible management options are urgently needed to address individual patient goals and the soaring impact on chronic disease and more broadly, healthcare systems

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Retatrutide Side Effects & Safety Data (2026) Trial incidence for retatrutide (reta) side effects GI rates, dysesthesia, and class-level safety concerns