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Circulation (2011) 124(21):233849

Once approved down the road, the safety profile observed in trials will guide real-world use of the drug, who can take it, and what additional measures might be necessary to protect patients

3.3 PI3K/Akt pathway GLP-1RAs can also function through the Phosphoinositide 3-kinases (PI3K)/AKT pathway (6567)

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The exendin 939 concentration used in this experiment was approximately 30 times higher than its IC 50 value for CAP-induced TRPV1 activation, indicating the mode-selective characteristics of exendin 939