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Patients switching from Wegovy to orforglipron had a change of -0.1 kg versus a 9.4 kg gain for placebo
Liver and heart disease
Variants in FTO , the fat-mass and obesity-associated gene, or in GLP1R , the receptor gene these compounds act on, shape the metabolism underneath any prescription
Watch for: Sudden pain in the upper stomach, especially after eating fatty food Fever, feeling sick, vomiting Thyroid tumours (seen in animal studies) In animal tests, some GLP-1 medicines were linked to a type of thyroid cancer called medullary thyroid carcinoma (MTC)
A: Because GLP-1 medication indications have expanded, pharmacists, as drug therapy experts, have a strong role to play in their medication management