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Consistent with the transcriptomic findings, proteomic analysis of liver from Gclc KO mice revealed that most significantly elevated proteins in Gclc KO liver were encoded by NRF2 target genes, including the canonical NRF2 target NQO1 (NAD(P)H Quinone Dehydrogenase 1) (Fig

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This test utilizes an extract from horseshoe crab blood that coagulates in the presence of endotoxins

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Its upregulation is significantly associated with poor patient prognosis (77)