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Many compounds that looked effective in animals later failed human trials or revealed safety concerns

The agency declined to evaluate three of them, writing that the nominations did not include sufficient information and that it did not identify clinical studies using BPC-157 in these populations. The 68-page review is entirely about ulcerative colitis, because thats the only proposed use with any human trial behind it

Preclinical studies suggest it promotes angiogenesis (new blood vessel formation), collagen synthesis, and modulation of nitric oxide pathwayskey steps in tissue repair

2e and f)

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N-acetylcysteine (NAC) has been one of the most studied in addiction contexts, especially for cocaine, cannabis, and alcohol use