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8 weeks (2 vials): 6 mL 1 10 mL bottle 12 weeks (4 vials): 12 mL 2 10 mL bottles 16 weeks (5 vials): 15 mL 2 10 mL bottles Alcohol Swabs: One for the vial stopper + one for the injection site each day

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Given the smaller sample sizes available in non-European populations, we did not perform genome-wide association testing in these populations, and instead focused analyses on variants discovered as associated in the European GWAS

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Endothelial cell proliferation and angiogenic signalling (VEGFR2, eNOS pathways)

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