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its induction can release damage-associated molecular patterns and tumor antigens, thereby remodeling the tumor immune landscape (80)

Accessed Apr

Mitochondrial respiratory chain complex 1 is targeted by metformin and its inhibition is involved in AMP-activated protein kinase-independent regulation of hepatic gluconeogenesis by triggering alterations in cellular energy charge and redox state

These findings indicated a reduction in bone resorption rate and a decrease in mineral turnover by LC [7,8,9]

Nat Rev Endocrinol (2011) 8(3):16071

The primary outcome was time-to-first occurrence of major adverse cardiovascular events (MACE