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As GLP-1 receptor agonists, these peptide drugs mimic the incretin hormone GLP-1, enhancing glucose-dependent insulin secretion, suppressing glucagon release, delaying gastric emptying, and reducing appetite [9]

This combination offers potential for fibrosis regression in patients with MASH and subsequent advanced fibrosis (NCT03449446)

FOXO4-DRI represents a transformative breakthrough in senescence research that has fundamentally changed our understanding of cellular aging and opened unprecedented opportunities for studying age-related diseases and interventions

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