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oleifera leaves contain 28.7% crude protein alongside 7.1% fat, while the protein content exists as insoluble compounds that display poor in vitro digestibility (27)

Additional research has also demonstrated a bi-directional relationship

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Hazneci E, Karabulut AB, Ozturk C, Batcioglu K, Dogan G, Karaca S, et al

Tzang 2025 (18 RCTs): overweight/obesity regains +5.63 kg while type 2 diabetes regains +2.03 kg but rebounds harder on blood-sugar control (HbA1c +0.65 vs +0.25%)

In the metal ion chelation assay, laccase (29.5%) and trypsin (19.3%) exhibited significant activity, with pepsin showing fewer notable results