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It is primarily made up of three amino acids: glutamine, glycine and cysteine

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Antiviral ISG effectors were among the most highly induced and abundant proteins in the infected host cells, such as MX1, cGAS, OAS1-3, IFIT1-3, ISG15, FKBP4, PIGR, and UBE2L3/5, which function in sensing and degradation of viral RNA, inhibition of ribonucleocapsid uncoating, translation and promote the innate immune response (Table 1, Supplementary Table 3, and Figures 5A, 7A,B)

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