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What Evidence Says About Needle Length Short Needles Work Well for Most People Multiple clinical guidance and injection technique recommendations conclude: Short needles (4 mm) reliably reach subcutaneous fat in adults of varied body mass indexes when proper technique is used, without needing to pinch the skin

The primary end point was the percent change in low density lipoprotein cholesterol at twenty four weeks

Patients may experience localized erythema, pruritus, swelling, or mild induration

PMC 9328668

The preceding Phase 2 trial enrolled 338 adults with a body mass index of at least 30 (or 27 with a weight-related condition) and ran for 48 weeks