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He and his partner, Angela Cleveland, have been together for over 20 years

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Many people plateau at doses of 0.5-1.0 mg weekly, but clinical data shows additional weight loss can occur at higher dosesup to 2.4 mg weeklyif side effects remain manageable

No dose adjustment is required for hepatic impairment, though limited data exists for severe cirrhosis and specialist input should be sought for decompensated disease

(ii) de novo lipogenesis from excess carbohydrates (glucose and fructose)

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