We fused a signal peptide (SP) and a furin-cleavable sequence (FCS) to the upstream region of the Exe4 gene to enable Exe4 secretion from the edited liver
[11] [53] [54] [55] Reported adverse gastrointestinal effects of phentermine include constipation, diarrhea, dysgeusia, nausea, and xerostomia
In macrophages, reorganization of the actin cytoskeleton necessary for chemotaxis and phagocytosis requires MsrB1-dependent reduction of methionine-R-sulfoxide residues within actin (27)
It helps convert food into glucose, providing energy, and supports brain health by aiding in neurotransmitter production
References Aoun, A., Darwish, F., & Hamod, N
this dysbiotic state facilitates systemic translocation of toxins (e.g., LPS), consequently exacerbating OA pathology (Kurz et al., 2025)