Clinical studies have found (Peter et al., 2013) that the combined intake of isoflavones and flavan-3-ols improves vascular function and arterial stiffness in postmenopausal patients with type 2 diabetes, thereby slowing disease progression
Given the limited number of human clinical trials (only three published), the full side effect profile may not be completely characterized
Th1 cells are the predominant Th cell subset to produce GM-CSF, which can upregulate macrophage/monocyte-derived dendritic cells (Mo-DCs) numbers via GM-CSFR signaling (67)
[NAPQI toxicity studies - see full reference list] 77-79
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