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Results at 72 weeks: Placebo: 3.1% weight loss Tirzepatide 5 mg: 16.0% weight loss (35.3 pounds average) Tirzepatide 10 mg: 21.4% weight loss (49.7 pounds average) Tirzepatide 15 mg: 22.5% weight loss (52.3 pounds average) The percentage of participants achieving 5% or more weight loss was 89% (5 mg), 96% (10 mg), and 96% (15 mg)

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Additionally, a post-hoc compiler average causal effect analysis was performed to estimate the influence of treatment adherence on outcomes

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Extended treatment with 5-amino-1MQ post-injury further amplified these effects [7]