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Rhoades, PhD, of MedVal Scientific Information Services, LLC, for providing editorial assistance

Segev has served as a consultant for or received speaking fees from pharmaceutical and healthcare companies AstraZeneca, Behring, CareDx, CSL, Jazz Pharmaceuticals, Mallinckrodt, Novavax, Novartis, Optum Health Education, Sanofi, Thermo-Fisher Scientific, Transmedics, and Veloxis

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As patients experience significant weight reductionwhich can be substantial in clinical trials, particularly at higher doses in patients with obesitymetabolic adaptations occur, including changes in blood pressure regulation and cardiovascular dynamics

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J Hepatol 2024;81:492-542