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The growing number of obese individuals due to several chronic disorders, changing lifestyle habits, rapid urbanization and digitalization fostering sedentary lifestyles

doi: 10.1038/cdd.2012.74

10.1016/j.neuroscience.2022.06.038 Neuroscience 12 BenarrochE

Use Cases: When Each Route Fits Topical GHK-Cu -- Localized Skin and Hair Goals The evidence supports topical use for: Facial aging and wrinkle reduction -- the most clinically validated use case, with multiple controlled studies Post-procedure recovery -- documented benefits after CO2 laser resurfacing Hair and scalp health -- community reports describe topical application to the scalp, though controlled hair-specific studies are limited General skin quality -- increased density, thickness, elasticity, and collagen documented in clinical studies Common audience: users primarily targeting cosmetic skin outcomes with the strongest available evidence base and the simplest application method

Whats particularly interesting is the strong interaction between TRPV1 and the endocannabinoid system: 1

So for now, this link in humans remains unknown