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In the initial 3 weeks, the observed mean pre-breakfast SMBG levels increased by 0.31 mmol/l from baseline in the IcoSema group and by 0.47 mmol/l in the semaglutide group but had returned to the baseline level by approximately week 6 in both treatment groups

Additionally, it is important to monitor blood sugar levels while taking this drug, as it may increase the risk for diabetes or pre-diabetes

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Curr Top Microbiol Immunol 358:291321 Yang Y, Li W, Sun Y, Han F, Hu C-AA, Wu Z (2015) Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells