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A combination of an ACE-I with an ARB is not recommended due to a lack of evidence for additional cardiovascular benefits and an increased risk of adverse events, including hyperkalemia, hypotension, and acute kidney injury [125,126,127,128]

By week 12 to 16, when you reach therapeutic doses, appetite suppression should be substantial

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Future research will need to clarify effectiveness, safety, and how medications might fit alongside therapy and recovery supports