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(p-values: * = 0.05, ** = 0.01, *** = 0.001)

Penicillamine, a copper chelator used in Wilson disease, requires dose adjustment in hepatic impairment precisely because liver function determines the rate at which mobilized copper can be processed and excreted [10]

This duration allows side effects to emerge and resolve as adaptation occurs, provides time for subtle benefits to become apparent, and establishes baseline against which to compare higher doses

These polyps were enlarged lymphoid follicles with infiltrated large numbers of lymphocytes and plasma cells

However, many tick bites do not cause a bullseye rash