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Findings for expanded MACE were similar, both within each subgroup for semaglutide vs placebo and for interaction analyses between the two subgroups (Fig

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Delayed gastric emptying Semaglutide slows down the rate at which food leaves the stomach and moves into the small intestine

Promote energy metabolism*

In laboratory and animal studies, GLP-1 receptor agonists appear to reduce production of pro-inflammatory cytokines, including tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)

A meta-analysis of the effect of glucagon-like peptide-1 (736) amide on ad libitum energy intake in humans