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The most common hypersensitivity reactions were rash (1.0% versus 0.5% for REPATHA and placebo, respectively), eczema (0.4% versus 0.2%), erythema (0.4% versus 0.2%), and urticaria (0.4% versus 0.1%)

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During the course of imaging (20 min), mice received isoflurane/O 2 and were maintained at 37 C by the heated bed on the scanner

Some patients may maintain treatment at 1.7 mg if the 2.4 mg dose is not tolerated