These substances probably dont work, and they might not even be safe: Many physicians have concerns about the minimal regulations that supplements are subject to and have concerns about potential contamination of supplements, in particular supplements marketed for weight loss, with unsafe substances, Johnson-Rabbett says
95%CI 0.421.17), for those who were treated with such agents at enrolment, the HR was as low as 0.23 and statistically significant in the post-hoc testing (95%CI 0.050.97) (Lam et al., 2021)
Research has found GLP-1 medications associated with a 45% reduction in Alzheimers disease risk 32
The combination of lower LDL and triglycerides while maintaining or slightly raising HDL ('good cholesterol') represents a favorable shift in cardiovascular risk factors
So we might look at that in more detail
Compared to patients treated with sodium-dependent glucose transporters 2 (SGLT2) inhibitors as monotherapy, those receiving GLP-1RAs for type 2 diabetes exhibited a significantly increased risk of thyroid hyperplasia and thyroid cancer [22]