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J Mol Neurosci 59(4):544553

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They proposed that the absence of a mechanism to restore alterations in methylation/demethylation pattern after an environmental insult could result in an accumulation of 5mC and 5hmC during the course of AD [135]

Insulin resistance is also associated with other health conditions, such as polycystic ovary syndrome (PCOS), nonalcoholic fatty liver disease (NAFLD), and sleep apnea