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One clinical trial enrolled 73 eligible participants with normal but low B12 levels and inadequate initial response to selective serotonin reuptake inhibitors (SSRIs), who were randomly assigned to either a treatment group (antidepressants combined with B12 injections, n = 34) or a control group (antidepressants alone, n = 39)

In the first cycle, a normal saline solution (6 g/kg) of BPC157 was administered intravenously