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Groups 6 and 7 (HML1&HML2) received HML at doses that corresponded to 1/40 and 1/20 of the LD 50 , respectively (75 and 150 mg active ingredient/kg bwt, that equivalent to a human dose of 12- and 24 mg/kg bwt)

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These nanoparticles can alleviate retinal IR injury by targeting the ferroptosis pathway and oxidative stress

van den Berg, G., Frolich, M., Veldhuis, J.D

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In addition, the tumor inhibitory effects of sertraline can be further enhanced when combined with compounds causing mitochondrial dysfunction, e.g., rotenone, antimycin A, or the anti-malarial artemether in ser/gly-dependent breast cancer mouse models [34]