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Naunyn-Schmiedeberg S Archives of Pharmacology, 399 (1), 815832

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PGRMC1 dimerization is required for binding to EGFR Because PGRMC1 is known to interact with EGFR and to accelerate tumour progression 18 , we examined the effect of haem-dependent dimerization of PGRMC1 on its interaction with EGFR by using purified proteins