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Metabolic benefits become measurable, especially when combined with dietary changes, exercise, or a primary weight loss medication

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These compounds may influence neurotransmitters, stress response pathways, and cognitive processes such as focus, memory, and mood regulation

Since NF-B-driven transcription is a key regulator of pro-inflammatory cytokine expression, this blockade may account for the observed reductions in TNF- and IL-6 in LPS-stimulated models