Research shows high doses of glutathione administered intravenously can effectively reduce a marker of cell damage in nonalcoholic liver disease
More recently, spinocerebellar ataxia type 2 has also been linked to the presence of a transition polymorphism in the GSTO2 gene (rs2297235 A183G) which significantly correlates with the age at disease onset
In cell culture studies, exogenous Glutathione can be used to probe the cellular response to oxidative insults, investigate the mechanisms of drug resistance, or modulate redox-sensitive signaling pathways
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