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Dysfunction of the neurovascular unit in ischemic stroke and neurodegenerative diseases: an aging effect

In research settings, potential risks discussed for senolytic approaches include off-target cell stress, unintended effects on non-senescent cells, immune or inflammatory reactions, and organ-specific toxicity depending on exposure and route

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The safety profile of AOD-9604 is favorable compared to many metabolic interventions, with clinical trials involving approximately 900 participants demonstrating good tolerability and minimal side effects

It is usually present in animal products, especially dairy products, poultry, eggs, and fish