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This proteolytic cleavage induces conformational changes that favors S-protein recognition by host cell membrane proteases (i.e., TMPRSS2, CTSL)

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Hydrogen peroxide is also one of the earliest signaling molecules involved in wound-signaling pathways, serving as a local signal for hypersensitive cell death and cell wall stiffening events, and as a mobile signal that stimulates defense-genes in adjacent cells (Orozco-Cardenas et al

[DOI] [PubMed] [Google Scholar] 110.Traber J., Suter M., Walter P., Richter C