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Both population and in vivo evidence indicate that oral Vitamin D supplementation increases cathelicidin levels in specific skin lesions, while topical Vitamin D analogues (e.g., calcipotriol) similarly enhance hCAP18/LL-37 expression in wound models, suggesting that correcting Vitamin D axis hyporesponsiveness may help reverse the age-associated phenotype of AMP deficiency and susceptibility [243, 244]

Entrainment of the circadian clock in the liver by feeding

Additionally, this effect was reversed by administration of the ROS scavenger N-acetylcysteine (NAC) (Fig

R., Liu, C

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Surgical resection remains challenging due to the aggressive nature of GBM and the difficulty in defining their margins [3]