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Fatty acid synthesis is further facilitated by the availability of NADPH, a cofactor required for lipogenesis and available due to the commitment to the PPP instead of glycolysis (131)

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USA 115 , 24732477 (2018)

CoA deficiency is expected to cause substantial abnormalities in cellular metabolism and can potentially explain the additional 9% weight loss in Cse / mice on the no-Cys diet compared to no-Trp + BSO diet (Fig