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Acknowledgments We would like to express our sincere gratitude to Professor Qiulun Lu and the members of his laboratory for their invaluable support in providing the necessary equipment and technical assistance for this study

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Skin changes usually come later because they depend on the gradual turnover of skin cells (NIH)

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The disrupted microbiome interacts with host immunity through mechanisms such as impaired TLR signaling, persistent inflammasome activation, and excessive protease release, all of which degrade extracellular matrix and hinder re-epithelialization

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