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1,15 Hyperglycemia-induced metabolic pathways Polyol pathway activation In a hyperglycemic state, excess glucose is shunted into the polyol pathway, where aldose reductase catalyzes its reduction to sorbitol, which in turn is oxidized to fructose by sorbitol dehydrogenase

We also excluded studies that lacked a clear link between the functional ingredient and cancer mechanismsfor instance, purely observational epidemiological studies reporting correlations between diet and cancer outcomes without investigating any biological mechanism were not included

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China's recent moves to expand exports to North America and Europe highlight its strategic pivot, though investments in higher-purity grades and novel delivery formats such as liposomal glutathione suggest a long-term goal of strengthening its global presence in premium markets

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