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The signalling profile of the monotreme GLP-1 peptides closely matched that of OXM with a bias towards pERK1/2, and to a lesser extent iCa 2+ , relative to cAMP (Fig
Biochemistry 48(11):24592467 Suzuki H, Kajimoto Y, Kumagai H (2002) Improvement of the bitter taste of amino acids through the transpeptidation reaction of bacterial gamma-glutamyltranspeptidase
It works by stimulating insulin release and reducing glucose production in the liver, leading to better control of blood sugar levels
Interestingly, PTEN-KD alone induced higher expression of both EPAC1 and EPAC2 compared to expression of BRAF V600E
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