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Fatty acid metabolism, necessary for supplying acetyl-CoA to the oxidative phosphorylation pathway, also relies on thiamine via B1-dependent 2-hydroxyacyl-CoA lyase, which is responsible for the alpha-oxidation of fatty acids, including phytanic acid [79]
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Activation of glucagon-like peptide-1 receptor inhibits tumourigenicity and metastasis of human pancreatic cancer cells via PI3K/Akt pathway