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In skeletal muscle, testosterone directly activates the androgen receptor to stimulate muscle protein synthesis via the Akt/mTOR pathway and inhibits key regulators of proteolysis, such as FoxO1 (116118)

It can also lead to dangerously low blood sugar, or hypoglycemia

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First, there is a need to clarify potential biological mechanisms by which incretin mimetics could directly lead to the development of PDAC

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