The involvement of OCTN1 in cancer metabolism, is probably unrelated to the poor ability of this transporter to mediate carnitine transport, however, it is interesting to know that OCTN1 is involved in the uptake of anti-cancer drugs (Table 1) such as Cytarabine (Zheng et al., 2016), mitoxantrone and doxorubicin (Okabe et al., 2008)
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We previously proposed transomic analysis to construct a global regulatory network for metabolism with multi-omics datasets 21,22,23
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