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Figure 1 3.2 Glucose metabolism was improved after antibiotics treatment in letrozole-induced PCOS mice After modeling by letrozole for 21 consecutive days, the glucose metabolism of mice in the four groups was evaluated by IPGTT, body weight, and fasting insulin level

Enhanced Blood Sugar Control Particularly beneficial for those with type 2 diabetes, semaglutide contributes to improved regulation of blood sugar levels by boosting insulin release and reducing glucose production in the liver

Their popularity may finally be making a dent in the nations obesity rate, which dropped from 39.9% in 2023 to 37% in 2025, according to Gallup

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Therefore, GLP-1RA drugs like liraglutide or semaglutide can counteract DPP-4 degradation, prolonging the GLP-1R signal and maintaining insulin secretion via the mTOR-dependent HIF-1 pathway (34)