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The suppression of SLC22A5 transcription in hyperglycemia results from the convergence of multiple metabolic stress pathways

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Our results showed that HFD induced an elevation in hepatic sulfate level suggesting an intensification of aerobic cysteine metabolism

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doi: 10.3389/fendo.2022.918467 181 TsuchiyaTOtoYAyabeTObataKMurakamiNNagaiT

A extrapolao dessas doses para humanos, utilizando os fatores de converso alomtricos padro (fator de 6,2 para o rato), fornece doses tericas da ordem de 1,6 g/kg em humanos