While effective for symptom control, NSAIDs carry risks of gastrointestinal ulceration and bleeding, cardiovascular events, renal impairment, and impaired bone and tendon healing
Because if you give it too much, you can dampen the signal
The arguments are its particular combination, such as antidepressant effect (Porsolts test, open field) [65] and region-specific influences on brain serotonin synthesis in rats given a particular increase in the substantia nigra [67] vs
Its mechanism is strictly enzymatic (NNMT inhibition)
It reduces SAM consumption, preserves its function as a methyl donor for epigenetic regulation, and further optimizes cellular metabolic efficiency
However, some people may experience some pain, swelling or redness at the injection site, and in much rarer cases headaches, itching or nausea