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Antioxidants: Such as quercetin and chlorogenic acid, which help reduce oxidative stress

10.1038/s41598-017-05541-4 104 WangW.MarinisJ

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Furthermore, since the instability of Ala 2 is caused by degradation of DPP-4, Ala 2 may not need to be changed if the peptide is fused with albumin or Fc domain (discussed later) for long-term activity, which creates a steric hindrance to prevent the enzyme from getting close

Many proteins are enzymes that catalyze the chemical reactions in metabolism

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