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doi: 10.1007/s12602-024-10223-5 39 ZhangHButoyiCYuanGJiaJ

In human vitiligo melanocytes (PIG3V) induced by hydrogen peroxide, baicalein increased the expression of Nrf2 and its downstream gene HO-1 in PIG3V cells, promoted the translocation of Nrf2 from cytoplasm to nucleus, indicating that the protective effect of baicalein on melanocytes depends on Nrf2 signaling pathway (Ma et al., 2018)

In the oxidative stress state in which a large amount of biological oxidants lead to an imbalance between oxidation and anti-oxidation in vivo, cellular oxidants activate various apoptosis inducers through certain transcription factors or directly lead to lipid peroxidation, protein and DNA damage, and enzyme expression disorders

Given its significance, ensuring the stability and efficacy of glutathione supplements is paramount

Research Applications 5-Amino-1MQ has been investigated in several areas of experimental research related to metabolism and enzymatic regulation

We proved that stable endogenous expression of GPX4 maintains the latent state of EBV