Using bacteriostatic water rather than sterile water matters significantly for shelf life
If Lilly encounters production problems, it could delay the launch even after approval
Taken together with the findings that utilization of esketamine as an antidepressant increases LAC levels [59], the fact that the decrease in LAC levels in subjects with MDD is independent of psychotropic drug treatment raises the possibility that increasing LAC levels may be needed to induce antidepressant effects
MacDonald A, Baxter J, Bessent R, et al
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